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Multi-stage emergency medicine logistics system optimization based on survival probability

Ke WANG, Yixin LIANG, Lindu ZHAO

《工程管理前沿（英文）》 2017年 第4卷 第2期   页码 221-228 doi: 10.15302/J-FEM-2017020

摘要： Using sudden cardiac deaths as an example and maximizing survival rate as the goal, this paper studies the influence of multi-stage medical logistics system optimization on the survival rate of sudden illness. A distribution model of survival is built, drone and ambulance arrival probability over time are discussed, a formula is proposed for maximum possible survival rate based on the probability of emergency medical logistics reaching the patient, and the results are analyzed using empirical data fitting distribution and numerical experiments performed with the model. The model is discussed as a reference point for management decision making by changing model parameters. Results show that compared to using current ambulance vehicles, ambulance drones delivering medical equipment for first aid on-site in emergencies can significantly increase survival rate, and the effect of collaborative multi-stage logistics optimization is better than that of any single stage logistics response optimization. Simulation results show that the medical rescue logistics service radius, speed, loading capacity and performance of ambulance drones impact the probability of survival, and there is an optimal service radius depending on the shape of probability distribution, which provides new information for management decisions.

关键词： emergency medicine logistics     ambulance drone     survival probability     critical illness    

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Study of blood exposure-related mental health illness among clinical nurses

null

《医学前沿（英文）》 2017年 第11卷 第1期   页码 147-151 doi: 10.1007/s11684-016-0481-8

摘要：

Nurses are subjected to high amount of stress in the medical setting, and work-related stress often leads to mental problems. This study aims to investigate the mental health status of nurses exposed to blood through needlestick injuries. A total of 302 nurses working in the hospital of Guangdong, China, participated in this study. Out of the 302 nurses, 140 did not experience any needlestick injuries during the previous week, whereas 162 nurses experienced needlestick injuries. The General Health Questionnaire (GHQ)-28 Standardized Questionnaire, which uses physical, anxiety, social function, and depression subscales, was used in this study. No significant difference between nurses exposed to blood and nurses not exposed to blood was found in terms of gender, age, length of employment, and civil status (P>0.05). Results from the GHQ-28 Standardized Questionnaire showed that 75.9% (123/162) of nurses exposed to blood were suspected to suffer from mental disorders, whereas 40% (56/140) of nurses not exposed to blood were suspected to suffer from mental disorders. The mean mental health scores of nurses exposed to blood and those not exposed were 8.73±7.32 and 5.69±5.70, respectively. From these results, we can conclude that blood exposure from needlestick injuries leads to higher prevalence of depression, anxiety, and stress symptoms in nurses. This finding highlights the importance of providing efficient, adequate, and appropriate support services after nurses are exposed to blood from needlestick injuries.

关键词： blood exposure     needlestick injuries     mental health     nurses    

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熵原理解读人类疾病和衰老

王志国

《工程（英文）》 2022年 第9卷 第2期   页码 22-26 doi: 10.1016/j.eng.2021.08.014

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Microbial biodegradation of plastics: Challenges, opportunities, and a critical perspective

《环境科学与工程前沿（英文）》 2022年 第16卷 第12期 doi: 10.1007/s11783-022-1596-6

摘要：

● Health hazards of plastic waste on environment are discussed.

关键词： Plastic-waste     Polymers     Health-hazards     Biodegradation     Microorganisms     Enzymes    

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Machine learning in building energy management: A critical review and future directions

《工程管理前沿（英文）》 2022年 第9卷 第2期   页码 239-256 doi: 10.1007/s42524-021-0181-1

摘要： Over the past two decades, machine learning (ML) has elicited increasing attention in building energy management (BEM) research. However, the boundary of the ML-BEM research has not been clearly defined, and no thorough review of ML applications in BEM during the whole building life-cycle has been published. This study aims to address this gap by reviewing the ML-BEM papers to ascertain the status of this research area and identify future research directions. An integrated framework of ML-BEM, composed of four layers and a series of driving factors, is proposed. Then, based on the hype cycle model, this paper analyzes the current development status of ML-BEM and tries to predict its future development trend. Finally, five research directions are discussed: (1) the behavioral impact on BEM, (2) the integration management of renewable energy, (3) security concerns of ML-BEM, (4) extension to other building life-cycle phases, and (5) the focus on fault detection and diagnosis. The findings of this study are believed to provide useful references for future research on ML-BEM.

关键词： building energy management     machine learning     integrated framework     knowledge evolution    

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Reducing environmental impacts through socioeconomic transitions: critical review and prospects

《环境科学与工程前沿（英文）》 2023年 第17卷 第2期 doi: 10.1007/s11783-023-1624-1

摘要：

● Reducing environmental impacts through socioeconomic structural transitions.

关键词： Environmental pressures     Environmental impacts     Nexus     Supply chains     Trade     Coupled systems    

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Advances in airborne microorganisms detection using biosensors: A critical review

《环境科学与工程前沿（英文）》 2021年 第15卷 第3期 doi: 10.1007/s11783-021-1420-8

摘要：

Humanity has been facing the threat of a variety of infectious diseases. Airborne microorganisms can cause airborne infectious diseases, which spread rapidly and extensively, causing huge losses to human society on a global scale. In recent years, the detection technology for airborne microorganisms has developed rapidly; it can be roughly divided into biochemical, immune, and molecular technologies.

关键词： Biosensor     Airborne microorganisms     Microbiological detection technology    

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Effects of critical geometric parameters on the optical performance of a conical cavity receiver

Hu XIAO, Yanping ZHANG, Cong YOU, Chongzhe ZOU, Quentin FALCOZ

《能源前沿（英文）》 2019年 第13卷 第4期   页码 673-683 doi: 10.1007/s11708-019-0630-2

摘要： The optical performance of a receiver has a great influence on the efficiency and stability of a solar thermal power system. Most of the literature focuses on the optical performance of receivers with different geometric shapes, but less research is conducted on the effects of critical geometric parameters. In this paper, the commercial software TracePro was used to investigate the effects of some factors on a conical cavity receiver, such as the conical angle, the number of loops of the helical tube, and the distance between the focal point of the collector and the aperture. These factors affect the optical efficiency, the maximum heat flux density, and the light distribution in the conical cavity. The optical performance of the conical receiver was studied and analyzed using the Monte Carlo ray tracing method. To make a reliable simulation, the helical tube was attached to the inner wall of the cavity in the proposed model. The results showed that the amount of light rays reaching the helical tube increases with the increasing of the conical angle, while the optical efficiency decreases and the maximum heat flux density increases. The increase in the number of loops contributed to an increase in the optical efficiency and a uniform light distribution. The conical cavity receiver had an optimal optical performance when the focal point of the collector was near the aperture.

关键词： parabolic collector     conical cavity receiver     critical geometric parameters     optical performance    

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MHD effect on the critical temperature differences of oscillatory thermocapillary convection in two-layer

Hulin HUANG, Xiaoming ZHOU,

《能源前沿（英文）》 2010年 第4卷 第2期   页码 155-160 doi: 10.1007/s11708-009-0063-4

摘要： The effect of different directional magnetic fields on critical temperature differences of oscillatory thermocapillary convection in a rectangular cavity with differentially heated side walls filled with two viscous, immiscible, incompressible fluids is simulated in the absence of gravity. In this two-layer fluid system, the upper layer fluid is the electrically non-conducting encapsulant boron oxide (BO), while the lower one is the electrically conducting molten indium phosphide (InP). The interface between the two fluids is assumed to be flat and non-deformable. The computational results show that all the magnetic fields along the , and directions can delay the transition from steady convection to oscillatory convection, and critical temperature differences increase with an increasing Hartmann number. Furthermore, the effect of a magnetic field along the direction is strongest, followed by that along the direction, and that along the direction is the weakest for the same intensity of the magnetic field.

关键词： magnetohydrodynamic     magnetic fields     thermocapillary convection     critical temperature difference     oscillatory convection     two-layer fluid system    

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Adsorption behavior of antibiotic in soil environment: a critical review

Shiliang WANG,Hui WANG

《环境科学与工程前沿（英文）》 2015年 第9卷 第4期   页码 565-574 doi: 10.1007/s11783-015-0801-2

摘要： Antibiotics are used widely in human and veterinary medicine, and are ubiquitous in environment matrices worldwide. Due to their consumption, excretion, and persistence, antibiotics are disseminated mostly via direct and indirect emissions such as excrements, sewage irrigation, and sludge compost and enter the soil and impact negatively the natural ecosystem of soil. Most antibiotics are amphiphilic or amphoteric and ionize. A non-polar core combined with polar functional moieties makes up numerous antibiotic molecules. Because of various molecule structures, physicochemical properties vary widely among antibiotic compounds. Sorption is an important process for the environment behaviors and fate of antibiotics in soil environment. The adsorption process has decisive role for the environmental behaviors and the ultimate fates of antibiotics in soil. Multiply physicochemical properties of antibiotics induce the large variations of their adsorption behaviors. In addition, factors of soil environment such as the pH, ionic strength, metal ions, and organic matter content also strongly impact the adsorption processes of antibiotics. Review about adsorption of antibiotics on soil can provide a fresh insight into understanding the antibiotic-soil interactions. Therefore, literatures about the adsorption mechanisms of antibiotics in soil environment and the effects of environment factors on adsorption behaviors of antibiotics in soil are reviewed and discussed systematically in this review.

关键词： adsorption     antibiotics     environment factors     soil    

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Experimental study of critical flow of water at supercritical pressure

Yuzhou CHEN, Chunsheng YANG, Shuming ZHANG, Minfu ZHAO, Kaiwen DU, Xu CHENG

《能源前沿（英文）》 2009年 第3卷 第2期   页码 175-180 doi: 10.1007/s11708-009-0029-6

摘要： Experimental studies of the critical flow of water were conducted under steady-state conditions with a nozzle 1.41 mm in diameter and 4.35 mm in length, covering the inlet pressure range of 22.1-26.8 MPa and inlet temperature range of 38-474°C. The parametric trend of the flow rate was investigated, and the experimental data were compared with the predictions of the homogeneous equilibrium model, the Bernoulli correlation, and the models used in the reactor safety analysis code RELAP5/MOD3.3. It is concluded that in the near or beyond pseudo-critical region, thermal-dynamic equilibrium is dominant, and at a lower temperature, choking does not occur. The onset of the choking condition is not predicted reasonably by the RELAP5 code.

关键词： critical flow     supercritical water-cooled reactor(SCWR)     reactor safety     loss of coolant accident(LOCA)    

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Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

《环境科学与工程前沿（英文）》 2017年 第11卷 第1期 doi: 10.1007/s11783-017-0899-5

摘要： A combination of adsorption with ozonation proved best for dye removal. Toxicity of the textile effluents can be remarkably reduced by combined method. Wide scope for choice of natural materials for treatment of textile dyes. Intrusion of synthetic textile dyes in the ecosystem has been recognized as a serious issue worldwide. The effluents generated from textiles contain large amount of recalcitrant unfixed dyes which are regarded as emerging contaminants in the field of waste water study. Removal of various toxic dyes often includes diverse and complex set of physico-chemical, biological and advanced oxidation processes adopted for treatment. Adsorption in itself is a well-known technique utilized for treatment of textile effluents using a variety of adsorbents. In addition, ozonation deals with effective removal of dyes using high oxidising power of ozone. The review summarizes dye removal study by a combination of ozonation and adsorption methods. Also, to acquire an effective interpretation of this combined approach of treating wastewater, a thorough study has been made which is deliberated here. Results asserts that, with the combined ability of ozone and a catalyst/adsorbent, there is high possibility of total elimination of dyes from waste water. Several synthetically prepared materials have been used along with few natural materials during the combined treatment. However, considering practical applicability, some areas were identified during the study where work needs to be done for effective implementation of the combined treatment.

关键词： Adsorption     Ozonation     Catalytic Ozonation     Textile dyes     Mineralization    

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Interfacial induction and regulation for microscale crystallization process: a critical review

《化学科学与工程前沿（英文）》 2022年 第16卷 第6期   页码 838-853 doi: 10.1007/s11705-021-2129-8

摘要： Microscale crystallization is at the frontier of chemical engineering, material science, and biochemical research and is affected by many factors. The precise regulation and control of microscale crystal processes is still a major challenge. In the heterogeneous induced nucleation process, the chemical and micro/nanostructural characteristics of the interface play a dominant role. Ideal crystal products can be obtained by modifying the interface characteristics, which has been proven to be a promising strategy. This review illustrates the application of interface properties, including chemical characteristics (hydrophobicity and functional groups) and the morphology of micro/nanostructures (rough structure and cavities, pore shape and pore size, surface porosity, channels), in various microscale crystallization controls and process intensification. Finally, possible future research and development directions are outlined to emphasize the importance of interfacial crystallization control and regulation for crystal engineering.

关键词： interfacial crystallization     heterogeneous nucleation     supersaturation     micro/nanostructure     process control and intensification    

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Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal

《医学前沿（英文）》 2022年 第16卷 第5期   页码 784-798 doi: 10.1007/s11684-021-0911-0

摘要： More than 85% of patients with uveal melanoma (UM) carry a GNAQ or GNA11 mutation at a hotspot codon (Q209) that encodes G protein α subunit q/11 polypeptides (Gαq/11). GNAQ/11 relies on palmitoylation for membrane association and signal transduction. Despite the palmitoylation of GNAQ/11 was discovered long before, its implication in UM remains unclear. Here, results of palmitoylation-targeted mutagenesis and chemical interference approaches revealed that the loss of GNAQ/11 palmitoylation substantially affected tumor cell proliferation and survival in UM cells. Palmitoylation inhibition through the mutation of palmitoylation sites suppressed GNAQ/11Q209L-induced malignant transformation in NIH3T3 cells. Importantly, the palmitoylation-deficient oncogenic GNAQ/11 failed to rescue the cell death initiated by the knock down of endogenous GNAQ/11 oncogenes in UM cells, which are much more dependent on Gαq/11 signaling for cell survival and proliferation than other melanoma cells without GNAQ/11 mutations. Furthermore, the palmitoylation inhibitor, 2-bromopalmitate, also specifically disrupted Gαq/11 downstream signaling by interfering with the MAPK pathway and BCL2 survival pathway in GNAQ/11-mutant UM cells and showed a notable synergistic effect when applied in combination with the BCL2 inhibitor, ABT-199, in vitro. The findings validate that GNAQ/11 palmitoylation plays a critical role in UM and may serve as a promising therapeutic target for GNAQ/11-driven UM.

关键词： uveal melanoma     mutant GNAQ/11     palmitoylation     BCL2     combination target therapy    

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A critical review of the emerging research on the detection and assessment of microplastics pollution

《环境科学与工程前沿（英文）》 2022年 第16卷 第10期 doi: 10.1007/s11783-022-1563-2

摘要：

● Coastal and marine regions are the most studied for microplastic pollution.

关键词： Plastic pollution     Waste management     Global south     Sustainability     Marine pollution    

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标题 作者 时间 类型 操作

Multi-stage emergency medicine logistics system optimization based on survival probability

Ke WANG, Yixin LIANG, Lindu ZHAO

期刊论文

Study of blood exposure-related mental health illness among clinical nurses

null

期刊论文

熵原理解读人类疾病和衰老

王志国

期刊论文

Microbial biodegradation of plastics: Challenges, opportunities, and a critical perspective

期刊论文

Machine learning in building energy management: A critical review and future directions

期刊论文

Reducing environmental impacts through socioeconomic transitions: critical review and prospects

期刊论文

Advances in airborne microorganisms detection using biosensors: A critical review

期刊论文

Effects of critical geometric parameters on the optical performance of a conical cavity receiver

Hu XIAO, Yanping ZHANG, Cong YOU, Chongzhe ZOU, Quentin FALCOZ

期刊论文

MHD effect on the critical temperature differences of oscillatory thermocapillary convection in two-layer

Hulin HUANG, Xiaoming ZHOU,

期刊论文

Adsorption behavior of antibiotic in soil environment: a critical review

Shiliang WANG,Hui WANG

期刊论文

Experimental study of critical flow of water at supercritical pressure

Yuzhou CHEN, Chunsheng YANG, Shuming ZHANG, Minfu ZHAO, Kaiwen DU, Xu CHENG

期刊论文

Adsorption in combination with ozonation for the treatment of textile waste water: a critical review

Shraddha Khamparia,Dipika Kaur Jaspal

期刊论文

Interfacial induction and regulation for microscale crystallization process: a critical review

期刊论文

Palmitoylation of GNAQ/11 is critical for tumor cell proliferation and survival in GNAQ/11-mutant uveal

期刊论文

A critical review of the emerging research on the detection and assessment of microplastics pollution

期刊论文